Which version? Version 1.6 or version 1.75.14?

I know Gothic 3 as a game that is very stable, but runtime environments differ as not everyone uses the same operating system, hardware & drivers.

You are well-advised to upgrade to 1.75.14 plus one or two additional patches, such as the mouse-in-inventory fix. There is more than one way how to perform the update:
https://ad.gamersky.info/@steamcommunity.com/sharedfiles/filedetails/?id=922996693

Don't crash the game >:(

I play this game from 2005 onwards. Original CD with Patches and everthing you can do with modding. The only thing i have encounterd is the "Where is theGuru" Crash. And this only happens ones in a month