This is the ultimate "nothing box".

Even in beta this game, absolutely rocked! And with each patch or content update the game has been vastly improving. Oxygen Not Included is a game with objectives, but effectively you create your own adventure using chemistry and physics in a fun simulation. Of sorts. :-)

Expand your colony, fix one problem only to create another problem for you to fix. There is an endless number of guides floating on the internet with varying degrees of complexity and elegance; though in the end, it is all up to you.